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Reologic condition of the blood in white female rats with obturation of bile ducts, as well as microcirculation of the liver, small intestine and kidneys, the process of free radicals.
Remarkable change in reologic blood features as hiperviscosity and blood flow decrease have been revealed.
Changes in microcirculation are observed both in the intestine and in the kidneys and liver.In kidneys they are more marked. In obturation of bile ducts the intense of free radicals oxidation along with the decrease of antioxidant enzymes activity, particularly superoxide dismutase (SOD) is observed.
These changes indicate the involvement of the liver, small intestine and kidneys in the pathology of the development of multiple organ failure during obstruction of the bile ducts.